The answer to this question depends on your mattress’s condition and the size of the bed bug infestation. If there are holes or tears in the mattress, bed bugs and their eggs may be nested inside. So we usually recommend discarding the mattress in this case. But if your mattress is in good shape and the infestation isn’t severe, we carry mattress safe encasements and active guard liners. Both of these products are effective as preventative and proactive bed bug treatments.